Clinicopathological Features and Type of Surgery for Lynch Syndrome: Changes during the Past Two Decades
نویسندگان
چکیده
منابع مشابه
Clinicopathological Features and Type of Surgery for Lynch Syndrome: Changes during the Past Two Decades.
PURPOSE The Korean Hereditary Tumor Registry, the first and one of the largest registries of hereditary tumors in Korea, has registered about 500 families with hereditary cancer syndromes. This study evaluates the temporal changes in clinicopathologic features and surgical patterns of Lynch syndrome (LS) patients. MATERIALS AND METHODS Data on 182 unrelated LS patients were collected retrospe...
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Lynch syndrome (LS) is characterized by an autosomal dominant inheritance of the early onset of colorectal cancer (CRC) and endometrial cancer, as well as increased risk for several other cancers including gastric, urinary tract, ovarian, small bowel, biliary tract, and brain tumors. The syndrome is due to a mutation in one of the four DNA mismatch repair (MMR) genes MLH1, MSH2, MSH6, or PMS2. ...
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Changes in Earth's reflectance over the past two decades.
We correlate an overlapping period of earthshine measurements of Earth's reflectance (from 1999 through mid-2001) with satellite observations of global cloud properties to construct from the latter a proxy measure of Earth's global shortwave reflectance. This proxy shows a steady decrease in Earth's reflectance from 1984 to 2000, with a strong climatologically significant drop after 1995. From ...
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ژورنال
عنوان ژورنال: Cancer Research and Treatment
سال: 2016
ISSN: 1598-2998,2005-9256
DOI: 10.4143/crt.2015.092